6 Best GPUs for AI Inference in 2025

An In-Depth Comparison of Nvidia RTX 5090, RTX 4090, RTX A6000, RTX A4000, Tesla A100, and A40.

Introduction

AI inference demands high-performance GPUs with exceptional computing capabilities, efficiency, and support for advanced AI workloads. This blog compares the latest and most relevant GPUs for AI inference in 2025: RTX 5090, RTX 4090, RTX A6000, RTX A4000, Tesla A100, and Nvidia A40. We'll evaluate their performance based on tensor cores, precision capabilities, architecture, and key advantages and disadvantages.

1. NVIDIA RTX 5090

Architecture: Blackwell 2.0

Launch Date: Jan. 2025

Computing Capability: 10.0

CUDA Cores: 21,760

Tensor Cores: 680 5th Gen

VRAM: 32 GB GDDR7

Memory Bandwidth: 1.79 TB/s

Single-Precision Performance: 104.8 TFLOPS

Half-Precision Performance: 104.8 TFLOPS

Tensor Core Performance: 450 TFLOPS (FP16), 900 TOPS (INT8)

The highly anticipated RTX 5090 introduces the Blackwell 2.0 architecture, delivering a significant performance leap over its predecessor. With increased CUDA cores and faster GDDR7 memory, it’s ideal for more demanding AI workloads. While not yet widely adopted in enterprise environments, its price-to-performance ratio makes it a strong contender for researchers and developers.

2. NVIDIA RTX 4090

Architecture: Ada Lovelace

Launch Date: Oct. 2022

Computing Capability: 8.9

CUDA Cores: 16,384

Tensor Cores: 512 4th Gen

VRAM: 24 GB GDDR6X

Memory Bandwidth: 1.01 TB/s

Single-Precision Performance: 82.6 TFLOPS

Half-Precision Performance: 165.2 TFLOPS

Tensor Core Performance: 330 TFLOPS (FP16), 660 TOPS (INT8)

The RTX 4090, primarily designed for gaming, has proven its capability for AI tasks, especially for small to medium-scale projects. With its Ada Lovelace architecture and 24 GB of VRAM, it’s a cost-effective option for developers experimenting with deep learning models. However, its consumer-oriented design lacks enterprise-grade features like ECC memory.

3. NVIDIA RTX A6000

Architecture: Ampere

Launch Date: Apr. 2021

Computing Capability: 8.6

CUDA Cores: 10,752

Tensor Cores: 336 3rd Gen

VRAM: 48 GB GDDR6

Memory Bandwidth: 768 GB/s

Single-Precision Performance: 38.7 TFLOPS

Half-Precision Performance: 77.4 TFLOPS

Tensor Core Performance: 312 TFLOPS (FP16)

The RTX A6000 is a workstation powerhouse. Its large 48 GB VRAM and ECC support make it perfect for training large models. Although its Ampere architecture is older compared to Ada and Blackwell, it remains a go-to choice for professionals requiring stability and reliability in production environments.

4. NVIDIA RTX A4000

Architecture: Ampere

Launch Date: Apr. 2021

Computing Capability: 8.6

CUDA Cores: 6,144

Tensor Cores: 192 3rd Gen

VRAM: 16 GB GDDR6

Memory Bandwidth: 448.0 GB/s

Single-Precision Performance: 19.2 TFLOPS

Half-Precision Performance: 19.2 TFLOPS

Tensor Core Performance: 153.4 TFLOPS

NVIDIA RTX A4000 is a powerful GPU designed for professional workstations, offering excellent performance for AI inference tasks. While A4000 is powerful, more recent GPUs like A100 and A6000 offer higher performance and larger memory options, which may be more suitable for very large-scale AI inference tasks.

5. NVIDIA Tesla A100

Architecture: Ampere

Launch Date: May. 2020

Computing Capability: 8.0

CUDA Cores: 6,912

Tensor Cores: 432 3rd Gen

VRAM: 40/80 GB HBM2e

Memory Bandwidth: 1,935GB/s 2,039 GB/s

Single-Precision Performance: 19.5 TFLOPS

Double-Precision Performance: 9.7 TFLOPS

Tensor Core Performance: FP64 19.5 TFLOPS, Float 32 156 TFLOPS, BFLOAT16 312 TFLOPS, FP16 312 TFLOPS, INT8 624 TOPS

The Tesla A100 is built for data centers and excels in large-scale AI training and HPC tasks. Its Multi-Instance GPU (MIG) feature allows partitioning into multiple smaller GPUs, making it highly versatile. The A100’s HBM2e memory ensures unmatched memory bandwidth, making it ideal for training massive AI models like GPT variants.

6. NVIDIA A40

Architecture: Ampere

Launch Date: Oct. 2020

Computing Capability: 8.6

CUDA Cores: 10,752

Tensor Cores: 336 3rd Gen

VRAM: 48 GB GDDR6

Memory Bandwidth: 696 GB/s

Single-Precision Performance: 37.4 TFLOPS

Half-Precision Performance: 37.4 TFLOPS

Tensor Core Performance: FP16 TFLOPS 149.7, TF32 TFLOPS 74.8, BF16 TFLOPS 149.7, INT8 TOPS 299.3, INT4 TOPS 598.7

The NVIDIA A40 accelerates the most demanding visual computing workloads from the data center, combining NVIDIA Ampere architecture RT Cores, Tensor Cores, and CUDA Cores with 48 GB of graphics memory. NVIDIA A40 GPU is a powerful and cost-effective solution for AI inference tasks, offering a good balance between performance and cost. While A40 is powerful, more recent GPUs like A100 and A6000 offer higher performance or larger memory options, which may be more suitable for very large-scale AI inference tasks

Technical Specifications

NVIDIA A100RTX A6000RTX 4090RTX 5090RTX A4000NVIDIA A40
ArchitectureAmpereAmpereAda LovelaceBlackwell 2.0AmpereAmpere
LaunchMay. 2020Apr. 2021Oct. 2022Jan. 2025Apr. 2021Oct. 2020
CUDA Cores6,91210,75216,38421,7606,14410,752
Tensor Cores432, Gen 3336, Gen 3512, Gen 4680 5th Gen192 3rd Gen336 3rd Gen
FP16 TFLOPs7838.782.6104.819.237.4
FP32 TFLOPs19.538.782.6104.819.237.4
FP64 TFLOPs9.71.21.31.60.61.2
Computing Capability8.08.68.910.08.68.6
Pixel Rate225.6 GPixel/s201.6 GPixel/s483.8 GPixel/s462.1 GPixel/s149.8 GPixel/s194.9 GPixel/s
Texture Rate609.1 GTexel/s604.8 GTexel/s1,290 GTexel/s1,637 GTexel/s299.5 GTexel/s584.6 GTexel/s
Memory40/80GB HBM2e48GB GDDR624GB GDDR6X32GB GDDR716 GB GDDR648 GB GDDR6
Memory Bandwidth1.6 TB/s768 GB/s1 TB/s1.79 TB/s448 GB/s696 GB/s
InterconnectNVLinkNVLinkN/ANVLinkNVLinkNVLink
TDP250W/400W250W450W300W140W300W
Transistors54.2B54.2B76B54.2B17.4B28.3B
Manufacturing7nm7nm4nm7nm8nm8nm

LLM Benchmarks from RunPod

LLM benchmarks

Conclusion

Choosing the right GPU for AI inference in 2025 depends on your workload and budget. The RTX 5090 leads with state-of-the-art performance but comes at a premium cost. For high-end enterprise applications, the Tesla A100 and RTX A6000 remain reliable choices. Meanwhile, the RTX A4000 offers a balance of affordability and capability for smaller-scale tasks. Understanding your specific needs will guide you to the optimal GPU for your AI inference journey.

GPU Server Recommendation

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  • CUDA Cores: 6,144
  • Tensor Cores: 192
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  • FP32 Performance: 19.2 TFLOPS
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  • CUDA Cores: 6144
  • Tensor Cores: 192
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  • FP32 Performance: 19.2 TFLOPS
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  • GPU: Nvidia A40
  • Microarchitecture: Ampere
  • CUDA Cores: 10,752
  • Tensor Cores: 336
  • GPU Memory: 48GB GDDR6
  • FP32 Performance: 37.48 TFLOPS
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  • GPU: Nvidia Quadro RTX A6000
  • Microarchitecture: Ampere
  • CUDA Cores: 10,752
  • Tensor Cores: 336
  • GPU Memory: 48GB GDDR6
  • FP32 Performance: 38.71 TFLOPS
  • Optimally running AI, deep learning, data visualization, HPC, etc.
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  • GPU: 2 x GeForce RTX 4090
  • Microarchitecture: Ada Lovelace
  • CUDA Cores: 16,384
  • Tensor Cores: 512
  • GPU Memory: 24 GB GDDR6X
  • FP32 Performance: 82.6 TFLOPS
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  • GPU: 4 x GeForce RTX 5090
  • Microarchitecture: Ada Lovelace
  • CUDA Cores: 20,480
  • Tensor Cores: 680
  • GPU Memory: 32 GB GDDR7
  • FP32 Performance: 109.7 TFLOPS

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  • GPU: Nvidia A100
  • Microarchitecture: Ampere
  • CUDA Cores: 6912
  • Tensor Cores: 432
  • GPU Memory: 40GB HBM2
  • FP32 Performance: 19.5 TFLOPS
  • Good alternativeto A800, H100, H800, L40. Support FP64 precision computation, large-scale inference/AI training/ML.etc

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  • GPU: Nvidia A100
  • Microarchitecture: Ampere
  • CUDA Cores: 6912
  • Tensor Cores: 432
  • GPU Memory: 80GB HBM2e
  • FP32 Performance: 19.5 TFLOPS
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